November 13, 2018
SCAHT AOP on developmental neurotoxicity and neurodegeneration
A newly published Adverse Outcome Pathway (AOP) from the SCAHT network (Florianne Tschudi-Monnet and Rex FitzGerald) links chemical effects during brain development (chronic NMDA receptor inhibition) to impairment of learning and memory and Alzheimer-like neurodegeneration. Such AOPs will be important for both researchers and regulators.