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octobre 1, 2020

OECD Integrated Approaches to Testing and Assessment (IATA): 8 new case studies

The Integrated Approaches to Testing and Assessment (IATA) Case Studies Project allows countries to share and explore the use of novel methodologies in Integrated Approaches to Testing and Assessment within a regulatory context.

Eight new cases have been published that illustrate diverse read-across approaches based on various type of data from New Approach Methodologies. A considerations document includes considerations topics such as Margins of Internal Exposure, Coverage of the key events in AOP, uncertainty on the use of non-endorsed AOPs  and advantage of the use of AOP networks.

AOP and read-across approaches for propylparaben, caffeine, chlorobenzenes, p-alkylphenols, branched carboxylic acids, methyl hexanoic acid, deguelin, strobilurins.

See further information.