Publications

Developmental neurotoxicity (DNT): A call for implementation of new approach methodologies for regulatory purposes: Summary of the 5th International Conference on DNT Testing

Celardo, I., Aschner, M., Ashton, R. S., Carstens, K. E., Cediel-Ulloa, A., Cöllen, E., Crofton, K. M., Debad, S. J., Dreser, N., Fitzpatrick, S., Fritsche, E., Gutsfeld, S., Hardy, B., Hartung, T., Hessel, E., Heusinkveld, H., Hogberg, H. T., Hsieh, J.-H., Kanda, Y., … Leist, M.

Altex,  1 Apr 2025


SKIG Report 2023-2024

Wittwehr, Clemens ; Audouze, Karine ; Burgdorf, Tanja ; Clerbaux, Laure-Alix ; Coerek, Emre ; Demuynck, Emmanuel ; Exner, Thomas ; Filipovska, Julija ; Fritsche, Ellen ; Geris, Liesbet ; Hench, Virginia ; Jeliazkova, Nina ; Karschnik, Travis ; Kuchovska, Eliska ; Maia Ladeira, Luiz Carlos ; Malinowska, Julia M ; Marinov, Evgeni ; Martens, Marvin ; Mertens, Birgit ; Nymark, Penny ; Schaffert, Alexandra ; Staumont, Bernard ; Tanabe, Shihori ; Tollefsen, Knut Erik ; Villeneuve, Daniel L ; Viviani, Barbara ;

European Commission,  1 Apr 2025


Publication Preview Developmental Neurotoxicity as a Case Example for a Six-Step Framework for the Sustainable Regulatory Implementation of NAMs

Jonathan Blum, Kristina Heck, Joyce de Paula Souza, Ellen Fritsche

Current Opinion in Toxicology,  1 Apr 2025


The SCAHT Adverse Outcome Pathway (AOP)_HUB: A hands-on platform for information exchange, sharing, and developing AOPs

Emre Coerek, Eliska Kuchovska, Lidwina Gerner, Lihini Nilma, Dan Villeneuve, Ellen Fritsche

Altex,  1 Apr 2025


Dual targeted lipid nanoparticles for enhanced DNA delivery and transfection of breast cancer cells

Lotter C, Stierli MA, Deepthi Puligilla R, Huwyler J

European Journal of Pharmaceutics and Biopharmaceutics,  1 Apr 2025


Consumer adoption of bioeconomy products

Joana Wensing; Angela Bearth; Vincenzina Caputo

21 Mar 2025


Nuclear hormone receptors control fundamental processes of human fetal neurodevelopment: Basis for endocrine disruption assessment

Koch K, Schlüppmann K, Hüsken S, Stark LM, Förster, Masjosthusmann S, Klose J, Dönmez A, Fritsche E

Environmental International,  20 Mar 2025


Hepatic and Extra-Hepatic Metabolism of Propylene Glycol Ethers in the Context of Central Nervous System Toxicity

Werner S, Pamies D, Zurich MG, Suter-Dick L

Toxicology,  8 Feb 2025


New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use

Bearth A, Roth N, Jansen T, Holden L, Čavoški A, Di Consiglio E, Hauzenberger I, Lee R, Mombelli E, Tcheremenskaia O, Wendt-Rasch L, Wilks MF

Environment International,  1 Feb 2025


Microphysiological models of the human placenta to study Brucella infections and antibiotic treatment during pregnancy

Odysseas Chaliotis, Julia A. Boos, Maren Ketterer, Christoph Dehio, Andreas Hierlemann

Placenta,  1 Feb 2025