Publications

New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Ardenkjær-Skinnerup, J., Baert, Y., Bajard, L., Blum, J., Brion, F., Coppola, L., Fini, J.-B., Fritsche, E., Holbech, H., Hurem, S., Jacobs, M. N., Johansson, H. K. L., Knapen, D., Lyche, J. L., Mai, P. N. T., Neuhaus, W., Nikolov, N. G. N., Nurani, A., Papageorgiou, K., Poulsen, R., Ramhøj, L., Řehůřková, E., Rosenmai, A. K., Rüegg, J., Sovadinová, I., Tait, S., Van de Pette, M., Vanhaecke, T., Vergauwen, L., Wedebye, E. B., Xu, E. G., Svingen, T.

Frontiers,  11 Fév 2026


Regulation of chemicals demands assessment of risks rather than identification of hazards only

Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.

Archives of Toxicology,  7 Fév 2026


Regulation of chemicals demands assessment of risks rather than identification of hazards only

Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.

Archives of Toxicology,  7 Fév 2026


New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project

Ardenkjær-Skinnerup J, Baert Y, Bajard L, Blum J, Brion F, Coppola L, Fini JB, Fritsche E, Holbech H, Hurem S, Jacobs MN, Johansson HKL, Knapen D, Koch K, Lyche JL, Mai PNT, Neuhaus W, Nikolov NG, Nurani A, Papageorgiou K, Poulsen R, Ramhøj L, Řehůřková E, Rosenmai AK, Rüegg J, Sovadinová I, Tait S, Van de Pette M, Vanhaecke T, Vergauwen L, Wedebye EB, Xu EG, Svingen T.

Frontiers in Toxicology,  3 Fév 2026


Developmental neurotoxicity evaluation of di(2-ethylhexyl) phthalate (DEHP) and three alternative plasticizers in human neurospheres

Kühne BA, Klose J, Seeger B, Illa M, Muñoz-Torrero D, Koch K, Fritsche E, Barenys M

Environment International Elsevier,  1 Jan 2026


Urinary concentrations of di-butyl phthalate isomers and reproductive hormonal parameters in adult men: A systematic review with dose-response meta-analysis

Tiberiu M. Nita, David Vernez, Pascal Wild, Nelly Pitteloud, Nancy B. Hopf

Environmental Toxicology and Pharmacology,  1 Jan 2026


Proposed key characteristics of neurotoxic chemicals

Lein PJ, Bowman AB, Cao Z, Carson M, Eskenazi B, Fritsche E, Harry GJ, Hartung T, Pessah IN, Slikker W Jr, Zeise L, Smith MT

NeuroToxicology Elsevier,  1 Jan 2026


Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination

Arianna Capucetti, Juliana Falivene, Chiara Pizzichetti, Irene Latino, Luca Mazzucchelli, Vivien Schacht, Urs Hauri , Andrea Raimond, Tommaso Virgilio , Alain Pulfer, Simone Mosole, Llorenç Grau- Roma, Wolfgang Bäumlr, Martin Palus, Louis Renner, Daniel Ruzek, Gabrielle Goldman Levy , Milena Foerster, Kamil Chahine, and Santiago F. Gonzalez

PNAS,  25 Nov 2025


Neurotoxicity of propylene glycol butyl ether: Multiomic evidence from human brainspheres

David Lopez-Rodriguez, David Pamies, Julien Boccard, Isabel Meister, Mathieu Galmiche, Tatjana Sajic, Estelle Maret, Noéline Héritier, Massimo Frangiamone, Aurélien Thomas, Nancy B. Hopf, Serge Rudaz, Marie-Gabrielle Zurich

Environment International,  22 Oct 2025


Exploring experiences of the regulatory toxicology system: system‑level promoters and inhibitors of new approach methodologies

Bearth A, Kopainsky B, Jones LB, Vist, G., Husøy, T, Svendsen C, Whaley P, Hoffmann S,· Ames HM, Solstad G, Bloch D, Čavoški A, Chiu WA, Davenport D, Davies HG, Giusti A, Hartung T, Kwon S, Osborne OJ, Rooney AA, Rousselle C, Sass JB, Wright FA, Mathisen GH

Archives of Toxicology,  18 Aoû 2025