The course is a two-day laboratory workshop in Leiden. This training instructs the attendee in best practices procedures for in silico and in vitro assays related to acute and chronic cardiotoxicity.

This two days hands-on training will cover practical use of respiratory in vitro 3D tissues and exposure devices to evaluate acute and repeated dose inhalation toxicity. To mimic systemic context, interconnection strategies of lung tissues will be presented.

The idea of this training is to illustrate various aspects of the OECD Good In Vitro Methods In Practice (GIVIMP) guidance document (STA 286) using assays/techniques/test systems that have been developed recently by the different trainers.

It aims to provide the participants with hands-on, practical skills in how to apply the ideas in GIVIMP in their daily work in the laboratory, and at the same time learn about modern techniques used for in vitro testing.

The course will introduce the use of models relevant for cosmetic ingredients, addressing properties like mutagenicity (Ames test and micronucleus), skin sensitizations, NOAEL, and others for human toxicity. The course will address hazard and exposure, such as skin permeation. New models, developed in the last year, will be also presented.

Abstracts for oral presentations and posters can be submitted until 14th June 2019.

Physiologically based pharmacokinetic (PBPK) modelling plays a crucial role in next generation (non-animal) risk evaluations to inform the design of in vitro studies and to convert the data obtained with in vitro models into human dose−response or potency information. The goal of the course is to acquaint participants with setting up PBPK models based on non-animal input parameters and to subsequently use these models to extrapolate in vitro bioassay data to human dose-response or potency information.

Street drugs, nanoparticles, human risk assessment, clinical toxicology, neonicotinoids, endocrine disruptors.

ISBM-11 aims to present new research and methods on biomarkers of exposure, effect and susceptibility to occupational and environmental agents, and to promote the use of biomonitoring data as part of a prevention strategy in workplaces and the general environment. It will thus be of interest to professionals involved in risk assessment, regulation and control through the use and interpretation of human biomonitoring data.

Toxicology Solutions for Global Public, Environmental, and Personal Health is the theme of the meeting. The Scientific Program Committee, working with IUTOX and other societies, has created an inclusive and diverse program that highlights excellence in science and practice of toxicology around the globe. An exciting slate of 20 Symposia, 4 Keynote Lectures, and 8 Continuing Education Courses will draw attendees from around the world with informative and inspiring strategies that can be implemented to improve human and environmental health in countries with both robust and developing research and regulatory enterprises.

This enjoyable workshop teaches you a new way of note-taking and will help you start thinking in images. Through drawing exercises and practice, this workshop will expand your existing note-taking skills to enhance learning, remembering, creative thinking and communication.